Intrauterine insemination (IUI) is an assisted reproduction method that improves a woman’s chance to achieve pregnancy by placing sperm directly inside her uterine cavity. Albeit simple, this concept can be an effective way of circumventing male fertility problems such impotence, premature ejaculation, or low sperm count or motility. It is also widely used in cases of unexplained infertility, polycystic ovary syndrome (PCOS), anovulation, or absence of a male partner.